How Much Does the Feline Leukemia Vaccine Cost in 2025?

This article was approved by Lemonade’s favorite vet, Dr. Stephanie Liff.

Feline leukemia (FeLV) is a serious viral infection that poses significant health risks to cats. In 2025, the average cost of the feline leukemia vaccine typically ranges from $25 to $70 per dose. 

The decision to vaccinate your cat can feel daunting, but understanding the details and benefits of the FeLV vaccine can make the process smoother. Let’s break down everything you need to know about the feline leukemia virus and vaccine. 

Or if you’re short on time, click below for a handy timeline of all the vaccinations your furry friend will need during kittenhood, plus a vaccination record template to help keep track of their vaccination schedule.

What is feline leukemia?

Feline leukemia is a retrovirus that affects cats’ immune systems, making them more susceptible to infections and diseases. The virus is transmitted through close contact with FeLV-infected cats, including grooming, bite wounds, and sharing food bowls or litter boxes. Cats at a higher risk of contracting FeLV include kittens, outdoor cats, and those living in multi-cat households.

Symptoms of feline leukemia can vary but often include:

• Anemia which means your cat has low red blood cells, often causing fatigue
• Loss of appetite 
• Weight loss 
• Persistent infections 

Unfortunately, there is no cure for FeLV, and it can lead to severe health issues such as lymphoma and other secondary infections. Early detection and preventive measures, like vaccination, are essential in managing the disease’s impact.

How does the feline leukemia vaccine work?

Just like other cat vaccinations, the feline leukemia vaccine works by stimulating the cat’s immune system to produce antibodies against the virus. There are two primary types of FeLV vaccines available:

1. Killed virus vaccines: Contain inactivated viruses that cannot cause disease, but still trigger an immune response
2. Recombinant vaccines: Use a small piece of the virus’s genetic material to induce immunity without causing illness

Both types of vaccines are effective in preventing FeLV infection. Your veterinarian can help you decide which type is best suited for your cat based on their health and lifestyle.

Besides FeLV, other vaccines, given based on the risk factors of the cat—like their lifestyle—could include Feline Chlamydia or (very rarely) Feline Bordetella. The “core” or essential vaccines your cat needs will typically include rabies and FVRCP (Feline Viral Rhinotracheitis, Feline Calicivirus, and Feline Panleukopenia). 

How much does the feline leukemia vaccine cost?

In 2025, the cost of the FeLV vaccine ranges from $25 to $70 per dose. Low-cost vaccination clinics or animal shelters may offer it at a reduced price, especially when included in a package with other essential pet vaccinations.

This cost can also vary depending on factors such as: 

• Where you live
• Whether it is administered at a veterinary clinic or a low-cost vaccination clinic
• If it’s part of a vaccination package

How often do cats need the feline leukemia vaccine?

There is no perfect, one-size-fits-all-paws kitten vaccination schedule. The feline leukemia vaccine has been considered a “non-core”, or nonessential, vaccination for cats. This means, that your vet may or may not recommend the vaccine depending on your kitty’s lifestyle, so it’s best to make these decisions together with your vet. 

However, Lemonade’s vet expert Dr. Liff advises that “The AAFP actually considers FeLV to be a core vaccine for pet cats, and advises that indoor cats receive it every 2 years while cats that go outside receive it annually.” 

If your cat is an ideal candidate to receive the FeLV vaccine, kittens should typically receive their first FeLV vaccine dose at around 8 to 12 weeks of age, followed by a booster shot 3 to 4 weeks later. 

After the initial series, adult cats typically require an annual booster to maintain immunity. 

However, the frequency of boosters may vary based on your cat’s risk of exposure and your veterinarian’s recommendations. Cats who spend extended periods of time outdoors may benefit from receiving the vaccine annually, whereas indoor cats may only need a booster once every two years.

Does pet insurance cover the cost of the feline leukemia vaccine?

Yes, pet insurance can usually include wellness coverage for vaccinations, including the FeLV vaccine, when they’re administered or supervised by a licensed vet. But the specifics will depend on the coverages you chose when signing up.

When you include the Puppy/Kitten Preventative Care Package on your Lemonade Pet policy, for example, your kitten will be eligible for coverage on up to six vaccines a year—which could include the initial feline leukemia vaccine and boosters.  

This package could also help cover the costs associated with microchip implantation, spay/neuter procedures, heartworm prevention, flea and tick prevention, heartworm tests, and more. 

For adult cats, Lemonade’s Preventative Care or Preventative+ Package also includes up to three vaccinations per year, which could help cover the costs of the FeLV vaccine.  

What are the potential side effects of the feline leukemia vaccine?

The FeLV vaccine is generally safe, but some cats may experience mild side effects. Common side effects include:

• Mild fever
• Lethargy
• Temporary loss of appetite
• Soreness at the injection site

In rare cases, cats may develop more severe reactions such as vomiting, diarrhea, or facial swelling. If you notice any unusual symptoms or severe reactions after your cat’s vaccination, contact your veterinarian immediately.

Before we go…

Vaccinating your cat against feline leukemia is a proactive step in safeguarding their health and well-being. Investing in pet insurance early in your kitten’s life can help provide your fur fam with extensive coverage—from non-core vaccines to unforeseen accidents and illnesses as they grow up into adult cats. 

Did you know that at Lemonade Pet you can cover your kitty with cat insurance from the time they’re two months old? 

Click below to get your quote started today.

FAQs

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A few quick words, because we <3 our lawyers: This post is general in nature, and any statement in it doesn’t alter the terms, conditions, exclusions, or limitations of policies issued by Lemonade, which differ according to your state of residence. You’re encouraged to discuss your specific circumstances with your own professional advisors. The purpose of this post is merely to provide you with info and insights you can use to make such discussions more productive! Naturally, all comments by, or references to, third parties represent their own views, and Lemonade assumes no responsibility for them. Coverage and discounts may not be available in all states.